Title : Hypoxia-inducible factor-2α and iron absorptive gene expression in Belgrade rat intestine.

Pub. Date : 2011 Jul

PMID : 21436314






2 Functional Relationships(s)
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1 The results showed that expression of hepatic hepcidin was significantly decreased and intestinal Hif2alpha was significantly increased in b/b and iron-fed b/b than +/+ rats. Iron endothelial PAS domain protein 1 Rattus norvegicus
2 Thus in b/b rats depressed liver hepcidin production and activated intestinal Hif2alpha starting at the C-pole resulted in increasing expression of iron transport genes, including DMT1 G185R, in an attempt to compensate for the anemia in Belgrade rats. Iron endothelial PAS domain protein 1 Rattus norvegicus