Title : Hydrodynamics-based transfection of the combination of betacellulin and neurogenic differentiation 1 DNA ameliorates hyperglycemia in mice with streptozotocin-induced diabetes.

Pub. Date : 2011 May

PMID : 21406008






3 Functional Relationships(s)
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1 Hydrodynamics-based transfection of the combination of betacellulin and neurogenic differentiation 1 DNA ameliorates hyperglycemia in mice with streptozotocin-induced diabetes. Streptozocin neurogenic differentiation 1 Mus musculus
2 Hepatic delivery of a combination of pcDNA-Neurod1 and pcDNA-Btc (experimental group) or pcDNA (control group) to mice with streptozocin-induced diabetes was achieved by HBT. hbt neurogenic differentiation 1 Mus musculus
3 CONCLUSIONS: The hypoglycemic effect of Neurod1 and Btc delivered by HBT was transient and associated with negligible complications. hbt neurogenic differentiation 1 Mus musculus