Title : Activation of protein kinase Tel1 through recognition of protein-bound DNA ends.

Pub. Date : 2011 May

PMID : 21402778






1 Functional Relationships(s)
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1 In vivo, Tel1 activation is enhanced in sae2Delta or mre11-3 mutants after camptothecin treatment; both of these mutants are defective in the removal of topoisomerase I from DNA. Camptothecin DNA-binding protein kinase TEL1 Saccharomyces cerevisiae S288C