| Protein Name | DNA-binding protein kinase TEL1 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 852190 |
| Gene Symbol | TEL1 |
| UniProt | P38110 (ATM_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 27 |
Description |
DNA-binding protein kinase TEL1 |
| Gene Summary |
Enables phosphatidylinositol-4-phosphate binding activity; protein serine/threonine kinase activity; and telomeric DNA binding activity. Involved in double-strand break repair; signal transduction in response to DNA damage; and telomere maintenance. Located in nucleus. Used to study ataxia telangiectasia and cancer. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); endocrine gland cancer (multiple); lung carcinoma (multiple); neurodegenerative disease (multiple); and senile cataract. Orthologous to human ATM (ATM serine/threonine kinase). [provided by Alliance of Genome Resources, Jul 2025] |
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