Title : Interaction of chondroitin sulfate with perforin and granzymes of cytolytic T-cells is dependent on pH.

Pub. Date : 1990 Dec 25

PMID : 2125503






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 At pH 5.2, granzyme A and perforin formed complexes with chondroitin sulfate A. Chondroitin Sulfates granzyme A Homo sapiens
2 Upon secretion of the granule contents induced by immobilized anti-CD3 antibodies, most granzyme A molecules remained complexed with the chondroitin sulfate A glycosaminoglycans, even if synthesis of intact proteoglycans was inhibited. Chondroitin Sulfates granzyme A Homo sapiens
3 Upon secretion of the granule contents induced by immobilized anti-CD3 antibodies, most granzyme A molecules remained complexed with the chondroitin sulfate A glycosaminoglycans, even if synthesis of intact proteoglycans was inhibited. Glycosaminoglycans granzyme A Homo sapiens