Title : Positive regulatory domain I (PRDM1) and IRF8/PU.1 counter-regulate MHC class II transactivator (CIITA) expression during dendritic cell maturation.

Pub. Date : 2011 Mar 11

PMID : 21216962






1 Functional Relationships(s)
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1 We show that PRDM1 co-repressors, G9a and HDAC2, are recruited to CIITApI, leading to a loss of histone acetylation and acquisition of histone H3K9 dimethylation and heterochromatin protein 1gamma (HP1gamma). ciitapi PR domain containing 1, with ZNF domain Mus musculus