Title : Use of a Schizosaccharomyces pombe PKA-repressible reporter to study cGMP metabolising phosphodiesterases.

Pub. Date : 2011 Mar

PMID : 21118717






2 Functional Relationships(s)
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1 As proof of this concept, we screened a collection of compounds previously identified as inhibitors of cAMP-specific PDE4 or PDE7 enzymes for their ability to inhibit the mammalian cGMP-specific PDE5A enzyme. Cyclic AMP phosphodiesterase 7A Homo sapiens
2 As proof of this concept, we screened a collection of compounds previously identified as inhibitors of cAMP-specific PDE4 or PDE7 enzymes for their ability to inhibit the mammalian cGMP-specific PDE5A enzyme. Cyclic GMP phosphodiesterase 7A Homo sapiens