PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21118717-6	2011	As proof of this concept, we screened a collection of compounds previously identified as inhibitors of cAMP-specific PDE4 or PDE7 enzymes for their ability to inhibit the mammalian cGMP-specific PDE5A enzyme.	Cyclic AMP	103-107	phosphodiesterase 4A	Homo sapiens	117-121	
21118717-6	2011	As proof of this concept, we screened a collection of compounds previously identified as inhibitors of cAMP-specific PDE4 or PDE7 enzymes for their ability to inhibit the mammalian cGMP-specific PDE5A enzyme.	Cyclic AMP	103-107	phosphodiesterase 7A	Homo sapiens	125-129	
21118717-6	2011	As proof of this concept, we screened a collection of compounds previously identified as inhibitors of cAMP-specific PDE4 or PDE7 enzymes for their ability to inhibit the mammalian cGMP-specific PDE5A enzyme.	Cyclic GMP	181-185	phosphodiesterase 4A	Homo sapiens	117-121	
21118717-6	2011	As proof of this concept, we screened a collection of compounds previously identified as inhibitors of cAMP-specific PDE4 or PDE7 enzymes for their ability to inhibit the mammalian cGMP-specific PDE5A enzyme.	Cyclic GMP	181-185	phosphodiesterase 7A	Homo sapiens	125-129	
21118717-8	2011	Further yeast-based assays show that BC76 inhibits PDE1, PDE4, PDE5, PDE8, PDE10 and PDE11, thus demonstrating the utility of this system for detecting and characterising inhibitors of either cAMP- or cGMP-metabolising PDEs.	bc76	37-41	3',5'-cyclic-nucleotide phosphodiesterase PDE1	Saccharomyces cerevisiae S288C	51-55	
21118717-8	2011	Further yeast-based assays show that BC76 inhibits PDE1, PDE4, PDE5, PDE8, PDE10 and PDE11, thus demonstrating the utility of this system for detecting and characterising inhibitors of either cAMP- or cGMP-metabolising PDEs.	bc76	37-41	phosphodiesterase 4A	Homo sapiens	57-61