Title : Lifespan extension in Caenorhabditis elegans by DMSO is dependent on sir-2.1 and daf-16.

Pub. Date : 2010 Oct 1

PMID : 20828537






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Lifespan extension in Caenorhabditis elegans by DMSO is dependent on sir-2.1 and daf-16. Dimethyl Sulfoxide Fork-head domain-containing protein;Forkhead box protein O Caenorhabditis elegans
2 This suggests that these genes downstream of DAF-16 might function in the lifespan extension properties of DMSO. Dimethyl Sulfoxide Fork-head domain-containing protein;Forkhead box protein O Caenorhabditis elegans
3 Genetic analysis using mutants of aging-related genes showed that lifespan extension in C. elegans by DMSO was dependent on sir-2.1 and daf-16 but not eat-2 or hsf-1. Dimethyl Sulfoxide Fork-head domain-containing protein;Forkhead box protein O Caenorhabditis elegans