| Protein Name | Forkhead box protein O |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 172981 |
| Gene Symbol | daf-16 |
| UniProt | O16850 (FOXO_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
256
Total Number of Articles : 308 |
Description |
Forkhead box protein O |
| Gene Summary |
Enables several functions, including 14-3-3 protein binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and enzyme binding activity. Involved in several processes, including defense response to bacterium; regulation of dauer larval development; and regulation of primary metabolic process. Located in cytosol and nucleus. Is expressed in several structures, including germ cell; germ line; gonad; hypodermis; and neurons. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to several human genes including FOXO1 (forkhead box O1) and FOXO3 (forkhead box O3). [provided by Alliance of Genome Resources, Jun 2025] |
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