| Protein Name | Forkhead box protein O |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 172981 |
| Gene Symbol | daf-16 |
| UniProt | O16850 (FOXO_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
256
Total Number of Articles : 308 |
Description |
Forkhead box protein O |
| Gene Summary |
Enables several functions, including 14-3-3 protein binding activity; beta-catenin binding activity; and enzyme binding activity. Involved in several processes, including defense response to other organism; regulation of dauer larval development; and regulation of transcription, DNA-templated. Located in cytosol and nucleus. Is expressed in several structures, including germ line; gonad; hypodermis; neurons; and somatic cell. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in alveolar rhabdomyosarcoma. Orthologous to several human genes including FOXO1 (forkhead box O1); FOXO3 (forkhead box O3); and FOXO4 (forkhead box O4). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |