Pub. Date : 2010 Dec 1
PMID : 20819075
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | However, we have shown that replacing the transmembrane and cytosolic regions of Jagged1 with a GPI (glycosylphosphatidylinositol) anchor, thereby targeting the protein to lipid rafts, did not enhance its shedding. | Glycosylphosphatidylinositols | jagged canonical Notch ligand 1 | Homo sapiens |
| 2 | We have also demonstrated that wild-type Jagged1 and a truncated polypeptide-anchored variant lacking the cytosolic domain were subject to similar constitutive and phorbol ester-regulated shedding. | Phorbol Esters | jagged canonical Notch ligand 1 | Homo sapiens |