Title : Concomitant enzyme-linked immunosorbent assay measurements of rat insulin, rat C-peptide, and rat proinsulin from rat pancreatic islets: effects of prolonged exposure to different glucose concentrations.

Pub. Date : 2010 Oct

PMID : 20702574






5 Functional Relationships(s)
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1 The precision study and the analysis of controls confirm that the validated ELISAs for rat C-peptide and proinsulin would be useful for further studies on the effects of preculture in different glucose concentrations. Glucose insulin 2 Rattus norvegicus
2 The higher the glucose concentration used during the 72-h culture period of rat islets, the higher insulin, C-peptide and proinsulin values were obtained in a subsequent short-term glucose-challenge experiment. Glucose insulin 2 Rattus norvegicus
3 The higher the glucose concentration used during the 72-h culture period of rat islets, the higher insulin, C-peptide and proinsulin values were obtained in a subsequent short-term glucose-challenge experiment. Glucose insulin 2 Rattus norvegicus
4 We also observed a nonequimolar, glucose-dependent secretion and content of rat insulin over rat C-peptide after culture at 11.1 and 28 mM glucose. Glucose insulin 2 Rattus norvegicus
5 We also observed a nonequimolar, glucose-dependent secretion and content of rat insulin over rat C-peptide after culture at 11.1 and 28 mM glucose. Glucose insulin 2 Rattus norvegicus