Title : Glutamate carboxypeptidase II: an amyloid peptide-degrading enzyme with physiological function in the brain.

Pub. Date : 2010 Nov

PMID : 20624932






2 Functional Relationships(s)
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1 Moreover, treatment of 8-mo-old transgenic mice for 1 mo with 2-(phosphonomethyl)-pentanedioic acid (10 mg/kg, intraperitoneally), a specific GCPII inhibitor, increased cerebral Abeta content. 2-(phosphonomethyl)pentanedioic acid folate hydrolase 1 Mus musculus
2 Moreover, treatment of 8-mo-old transgenic mice for 1 mo with 2-(phosphonomethyl)-pentanedioic acid (10 mg/kg, intraperitoneally), a specific GCPII inhibitor, increased cerebral Abeta content. 2-(phosphonomethyl)pentanedioic acid amyloid beta (A4) precursor protein Mus musculus