Pub. Date : 2010 Jun 15
PMID : 20529684
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A series of phenyl piperidine alpha-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP-13, are dual-sparing of MMP-1 and MMP-14 (MT1-MMP) and exhibit oral bioavailability in rats. | phenyl piperidine alpha-sulfone hydroxamate | matrix metallopeptidase 14 | Rattus norvegicus |
| 2 | A series of phenyl piperidine alpha-sulfone hydroxamate derivatives has been prepared utilizing a combination of solution-phase and resin-bound library technologies to afford compounds that are potent and highly selective for MMP-13, are dual-sparing of MMP-1 and MMP-14 (MT1-MMP) and exhibit oral bioavailability in rats. | phenyl piperidine alpha-sulfone hydroxamate | matrix metallopeptidase 14 | Rattus norvegicus |