Title : B lymphocyte-induced maturation protein 1 is a novel target gene of aryl hydrocarbon receptor.

Pub. Date : 2010 Jun

PMID : 20478695






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In this report, we show that expression of Blimp1 is induced by treatment with AhR ligands, such as methylcolanthrene (MC) in sebocyte and keratinocyte cell lines. methylcolanthrene PR domain containing 1, with ZNF domain Mus musculus
2 In this report, we show that expression of Blimp1 is induced by treatment with AhR ligands, such as methylcolanthrene (MC) in sebocyte and keratinocyte cell lines. Methylcholanthrene PR domain containing 1, with ZNF domain Mus musculus
3 This ligand-dependent induction of Blimp1 requires the expression of both AhR and ARNT, since transfection of siRNA specific to either AhR or ARNT significantly reduced Blimp1 mRNA in response to MC. Methylcholanthrene PR domain containing 1, with ZNF domain Mus musculus
4 This ligand-dependent induction of Blimp1 requires the expression of both AhR and ARNT, since transfection of siRNA specific to either AhR or ARNT significantly reduced Blimp1 mRNA in response to MC. Methylcholanthrene PR domain containing 1, with ZNF domain Mus musculus
5 Analysis using kinase inhibitors revealed that ligand-dependent induction of Blimp1, but not that of CYP1A1, is inhibited by staurosporine. Staurosporine PR domain containing 1, with ZNF domain Mus musculus
6 TPA, a potent activator of protein kinase C, increased Blimp1 mRNA but not CYP1A1. Tetradecanoylphorbol Acetate PR domain containing 1, with ZNF domain Mus musculus