Pub. Date : 2010 Jun 1
PMID : 20426484
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In addition to binding to a wide spectrum of target proteins to be transported, the PICK1 PDZ domain, via its conserved CPC motif, has also been shown to bind to lipid membranes. | cytidylyl-(3'-5')-cytidine | protein interacting with PRKCA 1 | Homo sapiens |
2 | However, the molecular basis of the CPC motif-mediated lipid membrane binding of the PICK1 PDZ domain is not known. | cytidylyl-(3'-5')-cytidine | protein interacting with PRKCA 1 | Homo sapiens |
3 | Here we show that the Cys residues in the CPC motif of the PICK1 PDZ domain forms reversible, intermolecular disulfide bonds under mild oxidation conditions. | cytidylyl-(3'-5')-cytidine | protein interacting with PRKCA 1 | Homo sapiens |