Pub. Date : 2010 Jun
PMID : 20369390
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin stimulates production of the antiapoptotic protein Bcl-2 via endothelin-1 and NFATc3 in SH-SY5Y cells. | Simvastatin | nuclear factor of activated T cells 3 | Homo sapiens |
| 2 | Simvastatin increased translocation of NFATc3 to the nucleus while reducing nuclear NFATc1 and having no effect on NFATc4. | Simvastatin | nuclear factor of activated T cells 3 | Homo sapiens |
| 3 | Treatment of cells with simvastatin stimulated binding of NFATc3 to the Bcl-2 promoter. | Simvastatin | nuclear factor of activated T cells 3 | Homo sapiens |
| 4 | We report novel findings showing that up-regulation of Bcl-2 by simvastatin involves ET-1 and the transcription factor NFATc3. | Simvastatin | nuclear factor of activated T cells 3 | Homo sapiens |