Protein Name | nuclear factor of activated T cells 3 |
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Organism | Homo sapiens |
Gene ID | 4775 |
Gene Symbol | NFATC3 |
UniProt | Q12968 (NFAC3_HUMAN), B5B2S0 (B5B2S0_HUMAN), B5B2S1 (B5B2S1_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
43
Total Number of Articles : 52 |
Description |
nuclear factor of activated T cells 3 |
Gene Summary |
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010] |
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