Protein Name nuclear factor of activated T cells 3
Organism Homo sapiens
Gene ID 4775
Gene Symbol

NFATC3

UniProt Q12968 (NFAC3_HUMAN), B5B2S0 (B5B2S0_HUMAN), B5B2S1 (B5B2S1_HUMAN)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 52
Description

nuclear factor of activated T cells 3

Gene Summary

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]

synonyms
  • nuclear factor of activated T-cells, cytoplasmic 3
  • NF-ATc3
  • T cell transcription factor NFAT4
Click to show/hide the synonyms
Properties