Title : A weak link in metabolism: the metabolic capacity for glycine biosynthesis does not satisfy the need for collagen synthesis.

Pub. Date : 2009 Dec

PMID : 20093739






2 Functional Relationships(s)
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1 In a previous paper, we pointed out that the capability to synthesize glycine from serine is constrained by the stoichiometry of the glycine hydroxymethyltransferase reaction, which limits the amount of glycine produced to be no more than equimolar with the amount of C 1 units produced. Glycine serine hydroxymethyltransferase 2 Homo sapiens
2 In a previous paper, we pointed out that the capability to synthesize glycine from serine is constrained by the stoichiometry of the glycine hydroxymethyltransferase reaction, which limits the amount of glycine produced to be no more than equimolar with the amount of C 1 units produced. Serine serine hydroxymethyltransferase 2 Homo sapiens