Title : Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.

Pub. Date : 2009 Aug 26

PMID : 19706858






1 Functional Relationships(s)
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1 Thirteen single-nucleotide polymorphisms on chromosome 10q24 within the CYP2C18-CYP2C19-CYP2C9-CYP2C8 cluster were associated with diminished clopidogrel response, with a high degree of statistical significance (P = 1.5 x 10(-13) for rs12777823, additive model). Clopidogrel cytochrome P450 family 2 subfamily C member 18 Homo sapiens