Title : Distribution of beta 1- and beta 2-adrenoceptors in mouse trachea and lung: a quantitative autoradiographic study.

Pub. Date : 1990 Jan

PMID : 1970491






2 Functional Relationships(s)
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1 Binding and quantitative autoradiography were used to detect [125I]-iodocyanopindolol (I-CYP) associated with beta 1- and beta 2-adrenoceptors in mouse tracheal epithelium and airway smooth muscle as well as in lung parenchymal tissue. [125i]-iodocyanopindolol hemoglobin, beta adult major chain Mus musculus
2 Direct measurement of tissue radioactivity also showed that specific I-CYP binding was competitively inhibited in the presence of the beta-adrenoceptor antagonists (-)-propranolol (non-selective), CGP 20712A (beta 1-selective) and ICI 118,551 (beta 2-selective). CGP 20712A hemoglobin, beta adult major chain Mus musculus