Title : The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish.

Pub. Date : 2009 Oct 30

PMID : 19615353






9 Functional Relationships(s)
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1 The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish. Tryptophan aryl hydrocarbon receptor 2 Danio rerio
2 The tryptophan photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) binds multiple AHRs and induces multiple CYP1 genes via AHR2 in zebrafish. 6-formylindolo(3,2-b)carbazole aryl hydrocarbon receptor 2 Danio rerio
3 FICZ at 10 nM was able to completely displace binding of 2,3,7,8-tetrachloro-1,6[3H]-dibenzo-p-dioxin to in vitro-expressed zebrafish AHR2 and AHR1B. 2,3,7,8-tetrachloro-1,6[3h]-dibenzo-p-dioxin aryl hydrocarbon receptor 2 Danio rerio
4 Inhibition of AHR2 translation in zebrafish embryos by an AHR2-specific morpholino antisense oligonucleotide decreased the induction of CYP1A and CYP1B1 by FICZ and by PCB126. Morpholinos aryl hydrocarbon receptor 2 Danio rerio
5 Inhibition of AHR2 translation in zebrafish embryos by an AHR2-specific morpholino antisense oligonucleotide decreased the induction of CYP1A and CYP1B1 by FICZ and by PCB126. Morpholinos aryl hydrocarbon receptor 2 Danio rerio
6 Inhibition of AHR2 translation in zebrafish embryos by an AHR2-specific morpholino antisense oligonucleotide decreased the induction of CYP1A and CYP1B1 by FICZ and by PCB126. Oligonucleotides aryl hydrocarbon receptor 2 Danio rerio
7 Inhibition of AHR2 translation in zebrafish embryos by an AHR2-specific morpholino antisense oligonucleotide decreased the induction of CYP1A and CYP1B1 by FICZ and by PCB126. Oligonucleotides aryl hydrocarbon receptor 2 Danio rerio
8 Inhibition of AHR2 translation in zebrafish embryos by an AHR2-specific morpholino antisense oligonucleotide decreased the induction of CYP1A and CYP1B1 by FICZ and by PCB126. 3,4,5,3',4'-pentachlorobiphenyl aryl hydrocarbon receptor 2 Danio rerio
9 Inhibition of AHR2 translation in zebrafish embryos by an AHR2-specific morpholino antisense oligonucleotide decreased the induction of CYP1A and CYP1B1 by FICZ and by PCB126. 3,4,5,3',4'-pentachlorobiphenyl aryl hydrocarbon receptor 2 Danio rerio