Title : Ceramide synthase 1 is regulated by proteasomal mediated turnover.

Pub. Date : 2009 Jul

PMID : 19393694






3 Functional Relationships(s)
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Protein Name
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1 We show that both endogenous and ectopically expressed CerS1 have rapid basal turnover and that diverse stresses including chemotherapeutic drugs, UV light and DTT can induce CerS1 turnover. Dithiothreitol ceramide synthase 1 Homo sapiens
2 We show that both endogenous and ectopically expressed CerS1 have rapid basal turnover and that diverse stresses including chemotherapeutic drugs, UV light and DTT can induce CerS1 turnover. Dithiothreitol ceramide synthase 1 Homo sapiens
3 This study reveals a novel and highly specific mechanism by which CerS1 protein levels are regulated and which directly impacts ceramide homeostasis. Ceramides ceramide synthase 1 Homo sapiens