Pub. Date : 1991 Aug
PMID : 1936105
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Probucol increases cholesteryl ester transfer protein activity in hypercholesterolaemic patients. | Probucol | cholesteryl ester transfer protein | Homo sapiens |
| 2 | Probucol administration to 10 hypercholesterolaemic patients increased the activity of the cholesteryl ester transfer protein (CETP) by 50%. | Probucol | cholesteryl ester transfer protein | Homo sapiens |
| 3 | Probucol administration to 10 hypercholesterolaemic patients increased the activity of the cholesteryl ester transfer protein (CETP) by 50%. | Probucol | cholesteryl ester transfer protein | Homo sapiens |
| 4 | The rise of CETP activity was significantly related with the plasma steady-state drug levels (r = 0.51, P less than 0.005), thus suggesting that probucol may directly stimulate CEPT synthesis and/or release. | Probucol | cholesteryl ester transfer protein | Homo sapiens |
| 5 | The rise of CETP activity was significantly related with the plasma steady-state drug levels (r = 0.51, P less than 0.005), thus suggesting that probucol may directly stimulate CEPT synthesis and/or release. | cept | cholesteryl ester transfer protein | Homo sapiens |
| 6 | Furthermore, CETP activity was inversely related with HDL-cholesterol levels, both in the whole series of 10 patients (r = -0.56, P less than 0.001) and, more so, in the single individuals (r between -0.77 and -0.97), thus suggesting that the reduction of plasma HDL-cholesterol levels is a direct consequence of CETP stimulation. | Cholesterol | cholesteryl ester transfer protein | Homo sapiens |
| 7 | Furthermore, CETP activity was inversely related with HDL-cholesterol levels, both in the whole series of 10 patients (r = -0.56, P less than 0.001) and, more so, in the single individuals (r between -0.77 and -0.97), thus suggesting that the reduction of plasma HDL-cholesterol levels is a direct consequence of CETP stimulation. | Cholesterol | cholesteryl ester transfer protein | Homo sapiens |