PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1936105-0 1991 Probucol increases cholesteryl ester transfer protein activity in hypercholesterolaemic patients. Probucol 0-8 cholesteryl ester transfer protein Homo sapiens 19-53 1936105-3 1991 Probucol administration to 10 hypercholesterolaemic patients increased the activity of the cholesteryl ester transfer protein (CETP) by 50%. Probucol 0-8 cholesteryl ester transfer protein Homo sapiens 91-125 1936105-3 1991 Probucol administration to 10 hypercholesterolaemic patients increased the activity of the cholesteryl ester transfer protein (CETP) by 50%. Probucol 0-8 cholesteryl ester transfer protein Homo sapiens 127-131 1936105-4 1991 The rise of CETP activity was significantly related with the plasma steady-state drug levels (r = 0.51, P less than 0.005), thus suggesting that probucol may directly stimulate CEPT synthesis and/or release. Probucol 145-153 cholesteryl ester transfer protein Homo sapiens 12-16 1936105-4 1991 The rise of CETP activity was significantly related with the plasma steady-state drug levels (r = 0.51, P less than 0.005), thus suggesting that probucol may directly stimulate CEPT synthesis and/or release. cept 177-181 cholesteryl ester transfer protein Homo sapiens 12-16 1936105-5 1991 Furthermore, CETP activity was inversely related with HDL-cholesterol levels, both in the whole series of 10 patients (r = -0.56, P less than 0.001) and, more so, in the single individuals (r between -0.77 and -0.97), thus suggesting that the reduction of plasma HDL-cholesterol levels is a direct consequence of CETP stimulation. Cholesterol 58-69 cholesteryl ester transfer protein Homo sapiens 13-17 1936105-5 1991 Furthermore, CETP activity was inversely related with HDL-cholesterol levels, both in the whole series of 10 patients (r = -0.56, P less than 0.001) and, more so, in the single individuals (r between -0.77 and -0.97), thus suggesting that the reduction of plasma HDL-cholesterol levels is a direct consequence of CETP stimulation. Cholesterol 267-278 cholesteryl ester transfer protein Homo sapiens 13-17