Title : Hyaluronan promotes the chondrocyte response to BMP-7.

Pub. Date : 2009 Jul

PMID : 19195913






1 Functional Relationships(s)
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1 RESULTS: The disruption of the hyaluronan-dependent pericellular matrix of chondrocytes resulted in diminished nuclear translocation of endogenous Smad1 and Smad4 in response to BMP-7; however, the nuclear translocation of Smad2 and Smad4 in these matrix-depleted chondrocytes in response to TGF-beta1 was not diminished. Hyaluronic Acid SMAD family member 2 Bos taurus