Title : Flow cytometry-based binding assay for GPR40 (FFAR1; free fatty acid receptor 1).

Pub. Date : 2009 Jan

PMID : 18927207






3 Functional Relationships(s)
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1 GPR40 is a G protein-coupled receptor (GPCR) whose endogenous ligands have recently been identified as medium- and long-chain free fatty acids (FFAs), and it is thought to play an important role in insulin release. medium- and long-chain free fatty acids free fatty acid receptor 1 Mus musculus
2 The FFAs that activate GPR40 competed with C1-BODIPY-C12 binding; thus, medium- to long-chain FFAs could compete, whereas short-chain FFAs and methyl linoleate had no inhibitory effect. C1-BODIPY-C12 free fatty acid receptor 1 Mus musculus
3 The FFAs that activate GPR40 competed with C1-BODIPY-C12 binding; thus, medium- to long-chain FFAs could compete, whereas short-chain FFAs and methyl linoleate had no inhibitory effect. methyl linoleate free fatty acid receptor 1 Mus musculus