Title : Adenovirus-mediated FKBP12.6 overexpression induces hypertrophy and apoptosis in cultured neonatal cardiomyocytes.

Pub. Date : 2009 Feb

PMID : 18759859






1 Functional Relationships(s)
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1 Rapamycin treatment downregulated the expression of p-ERK1/2, p38 MAPK and Bax in stimulated cardiomyocytes, with or without FKBP12.6 overexpression, and enhanced protein synthesis, but had no effect on DNA synthesis in cardiomyocytes. Sirolimus FKBP prolyl isomerase 1B Homo sapiens