Title : A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.

Pub. Date : 2008 Sep

PMID : 18725531






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Homology modeling of this putative PIP(2)-binding linker in Kv7.2 and Kv7.3 using the solved structure of Kir2.1 and Kir3.1 channels as templates predicts a structure of Kv7.2 and 7.3 very similar to the Kir channels, and to the seven-beta-sheet barrel motif common to other PIP(2)-binding domains. Phosphatidylinositol 4,5-Diphosphate potassium inwardly rectifying channel subfamily J member 3 Homo sapiens
2 Homology modeling of this putative PIP(2)-binding linker in Kv7.2 and Kv7.3 using the solved structure of Kir2.1 and Kir3.1 channels as templates predicts a structure of Kv7.2 and 7.3 very similar to the Kir channels, and to the seven-beta-sheet barrel motif common to other PIP(2)-binding domains. Phosphatidylinositol 4,5-Diphosphate potassium inwardly rectifying channel subfamily J member 3 Homo sapiens