Title : Metabolism and related human risk factors for hepatic damage by usnic acid containing nutritional supplements.

Pub. Date : 2008 Mar

PMID : 18274956






1 Functional Relationships(s)
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Protein Name
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1 Usnic acid was a relatively weak inhibitor of CYP2D6 and a potent inhibitor of CYP2C19 (the concentration eliciting 50% inhibition (IC(50)) = 9 nM) and CYP2C9 (IC(50) = 94 nM), with less potent inhibition of CYP2C8 (IC(50) = 1.9 microM) and CYP2C18 (IC(50) = 6.3 microM). usnic acid cytochrome P450 family 2 subfamily C member 18 Homo sapiens