Title : The role of histone deacetylases in asthma and allergic diseases.

Pub. Date : 2008 Mar

PMID : 18234319






1 Functional Relationships(s)
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1 HDAC2 expression and activity is reduced in lung macrophages, biopsy specimens, and blood cells from patients with severe asthma and smoking-induced asthma, as well as in patients with chronic obstructive pulmonary disease, perhaps accounting for the enhanced inflammation and reduced steroid responsiveness seen in these patients. Steroids histone deacetylase 2 Homo sapiens