Title : Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias.

Pub. Date : 2007 Nov 30

PMID : 17921453






1 Functional Relationships(s)
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1 FK506 increased the amplitude and decreased the frequency of SOICR in HEK293 cells expressing RyR2 with or without FKBP12.6, indicating that the action of FK506 on SOICR is independent of FKBP12.6. Tacrolimus FKBP prolyl isomerase 1B Homo sapiens