Title : Tel1 kinase and subtelomere-bound Tbf1 mediate preferential elongation of short telomeres by telomerase in yeast.

Pub. Date : 2007 Nov

PMID : 17917674






1 Functional Relationships(s)
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1 Tethering of the subtelomere binding protein Tbf1 to the artificial telomere in tel1Delta cells restored preferential telomerase action at short telomeres; thus, Tbf1 might function in parallel to Tel1, which has a crucial role in a TG-repeat-controlled pathway for the activation of telomerase at short telomeres. Thioguanine DNA-binding protein kinase TEL1 Saccharomyces cerevisiae S288C