Pub. Date : 2007 Jul
PMID : 17471173
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Western blotting revealed that cryptotanshinone significantly inhibited PI3K-p110gamma membrane translocation and phosphorylation of Akt (PI3K downstream effector protein) and ERK1/2 induced by C5a. | cryptotanshinone | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Mus musculus |
| 2 | Wortmannin significantly attenuated C5a-induced PI3K-p110gamma translocation, Akt and ERK1/2 phosphorylation. | Wortmannin | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Mus musculus |
| 3 | Furthermore, MIP-1alpha-induced cell migration and PI3K-p110gamma translocation were also inhibited by cryptotanshinone in a concentration-dependent manner. | cryptotanshinone | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Mus musculus |