Title : TRPM7 and TRPM2-Candidate susceptibility genes for Western Pacific ALS and PD?

Pub. Date : 2007 Aug

PMID : 17395433






3 Functional Relationships(s)
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1 In this review, we describe how the functional properties of TRPM7 and TRPM2 are interconnected with calcium (Ca(2+)) and magnesium (Mg(2+)) homeostasis, oxidative stress, mitochondrial dysfunction, and immune mechanisms, all principal suspects in neurodegeneration. Calcium transient receptor potential cation channel subfamily M member 7 Homo sapiens
2 In this review, we describe how the functional properties of TRPM7 and TRPM2 are interconnected with calcium (Ca(2+)) and magnesium (Mg(2+)) homeostasis, oxidative stress, mitochondrial dysfunction, and immune mechanisms, all principal suspects in neurodegeneration. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens
3 In this review, we describe how the functional properties of TRPM7 and TRPM2 are interconnected with calcium (Ca(2+)) and magnesium (Mg(2+)) homeostasis, oxidative stress, mitochondrial dysfunction, and immune mechanisms, all principal suspects in neurodegeneration. Magnesium transient receptor potential cation channel subfamily M member 7 Homo sapiens