Title : Tissue distribution and functional analyses of the constitutively active orphan G protein coupled receptors, GPR26 and GPR78.

Pub. Date : 2007 Jun

PMID : 17363172






2 Functional Relationships(s)
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1 Investigation of the functional activity of GPR26 and GPR78 via expression in HEK293 cells showed that both proteins are constitutively active and coupled to elevated cAMP production. Cyclic AMP G protein-coupled receptor 78 Homo sapiens
2 A comparison of the proteins revealed an atypical glutamine residue in GPR78 in place of the conserved arginine residue (R3.50) in the so-called DRY box. Glutamine G protein-coupled receptor 78 Homo sapiens