Title : Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs.

Pub. Date : 2007 May

PMID : 17333111






1 Functional Relationships(s)
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1 Levels of Ins1 and Ins2 mRNAs were severely decreased in response to CPA treatment as a result of degradation, and there was a concomitant increase in the level of IRE1 activation. cyclopiazonic acid insulin 2 Rattus norvegicus