Pub. Date : 2007 Jun 15
PMID : 17313373
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Similarly, K201 was able to suppress spontaneous Ca2+ release in FK506-treated HEK-293 cells co-expressing RyR2 and FKBP12.6. | K201 compound | FKBP prolyl isomerase 1B | Homo sapiens |
| 2 | Similarly, K201 was able to suppress spontaneous Ca2+ release in FK506-treated HEK-293 cells co-expressing RyR2 and FKBP12.6. | Tacrolimus | FKBP prolyl isomerase 1B | Homo sapiens |
| 3 | Furthermore, K201 suppressed spontaneous Ca2+ release in HEK-293 cells expressing RyR2 alone and in cells co-expressing RyR2 and FKBP12.6 with the same potency. | K201 compound | FKBP prolyl isomerase 1B | Homo sapiens |
| 4 | In addition, K201 inhibited [3H]ryanodine binding to RyR2-wt (wild-type) and an RyR2 mutant linked to ventricular tachycardia and sudden death, N4104K, in the absence of FKBP12.6. | K201 compound | FKBP prolyl isomerase 1B | Homo sapiens |