Pub. Date : 2006 Dec
PMID : 17141627
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Serotonin targets the DAF-16/FOXO signaling pathway to modulate stress responses. | Serotonin | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |
| 2 | Here we describe how serotonin (5HT) governs stress behavior by regulating DAF-2 insulin/IGF-1 receptor signaling to the DAF-16/FOXO transcription factor at the nexus of development, metabolism, immunity, and stress responses in C. elegans. | Serotonin | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |
| 3 | Here we describe how serotonin (5HT) governs stress behavior by regulating DAF-2 insulin/IGF-1 receptor signaling to the DAF-16/FOXO transcription factor at the nexus of development, metabolism, immunity, and stress responses in C. elegans. | Serotonin | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |
| 4 | Serotonin-deficient tph-1 mutants, like daf-2 mutants, exhibit DAF-16 nuclear accumulation and constitutive physiological stress states. | Serotonin | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |
| 5 | Exogenous 5HT and fluoxetine (Prozac) prevented DAF-16 nuclear accumulation in wild-type animals under stresses. | Serotonin | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |
| 6 | Exogenous 5HT and fluoxetine (Prozac) prevented DAF-16 nuclear accumulation in wild-type animals under stresses. | Fluoxetine | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |
| 7 | Exogenous 5HT and fluoxetine (Prozac) prevented DAF-16 nuclear accumulation in wild-type animals under stresses. | Fluoxetine | Fork-head domain-containing protein;Forkhead box protein O | Caenorhabditis elegans |