Title : Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation.

Pub. Date : 2006 Dec 13

PMID : 17124499






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 cGMP-inhibited cAMP phosphodiesterase 3A (PDE3A) is expressed in mouse oocytes, and its function is indispensable for meiotic maturation as demonstrated by genetic ablation. Cyclic GMP phosphodiesterase 3A, cGMP inhibited Mus musculus
2 Cell-free incubation of recombinant mouse PDE3A with PKB/Akt or cAMP-dependent protein kinase A catalytic subunits leads to phosphorylation of the PDE3A protein. Cyclic AMP phosphodiesterase 3A, cGMP inhibited Mus musculus
3 Cell-free incubation of recombinant mouse PDE3A with PKB/Akt or cAMP-dependent protein kinase A catalytic subunits leads to phosphorylation of the PDE3A protein. Cyclic AMP phosphodiesterase 3A, cGMP inhibited Mus musculus