Pub. Date : 2007 Jul
PMID : 17103462
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The C-peptide fragment EVARQ reduces glomerular hyperfiltration in streptozotocin-induced diabetic rats. | Streptozocin | insulin 2 | Rattus norvegicus |
| 2 | This study was designed to elucidate the effects of the C-peptide fragment EVARQ on kidney function, blood pressure and blood glucose levels in diabetic rats in vivo. | Blood Glucose | insulin 2 | Rattus norvegicus |
| 3 | Furthermore, blood pressure was only reduced in diabetic rats that were given C-peptide, whereas the blood glucose decreased in the diabetic groups that were given either C-peptide or EVARQ. | Blood Glucose | insulin 2 | Rattus norvegicus |
| 4 | CONCLUSIONS: The present study shows that administration of the C-peptide fragment EVARQ has similar effects on GFR and blood glucose levels as the intact C-peptide molecule, suggesting at least one active site within this region. | Glucose | insulin 2 | Rattus norvegicus |