Pub. Date : 1991 Jan
PMID : 1706603
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To elucidate the pathophysiological significance of endogenous atrial natriuretic polypeptide (ANP) in hypertension, we investigated the biosynthesis and secretion of ANP in deoxycorticosterone acetate (DOCA)-salt hypertensive rats and also examined the effect of passive immunization with monoclonal antibody raised against alpha-rat ANP on the development of hypertension in DOCA-salt rats. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 2 | To elucidate the pathophysiological significance of endogenous atrial natriuretic polypeptide (ANP) in hypertension, we investigated the biosynthesis and secretion of ANP in deoxycorticosterone acetate (DOCA)-salt hypertensive rats and also examined the effect of passive immunization with monoclonal antibody raised against alpha-rat ANP on the development of hypertension in DOCA-salt rats. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 3 | The plasma ANP level in DOCA-salt rats was significantly elevated in comparison to control rats. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 4 | These results suggest the augmented biosynthesis of ANP in the atrium and the oversecretion of ANP from the heart in DOCA-salt rats. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 5 | These results suggest the augmented biosynthesis of ANP in the atrium and the oversecretion of ANP from the heart in DOCA-salt rats. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 6 | The levels of ANP and ANPmRNA in the ventricle of DOCA-salt rats exhibited significant increases, compared with those in control rats, suggesting the induction of ANP gene expression in the ventricle of DOCA-salt hypertensive rats under pre/after overload. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 7 | The levels of ANP and ANPmRNA in the ventricle of DOCA-salt rats exhibited significant increases, compared with those in control rats, suggesting the induction of ANP gene expression in the ventricle of DOCA-salt hypertensive rats under pre/after overload. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 8 | The levels of ANP and ANPmRNA in the ventricle of DOCA-salt rats exhibited significant increases, compared with those in control rats, suggesting the induction of ANP gene expression in the ventricle of DOCA-salt hypertensive rats under pre/after overload. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |
| 9 | The levels of ANP and ANPmRNA in the ventricle of DOCA-salt rats exhibited significant increases, compared with those in control rats, suggesting the induction of ANP gene expression in the ventricle of DOCA-salt hypertensive rats under pre/after overload. | Desoxycorticosterone Acetate | natriuretic peptide A | Rattus norvegicus |