| Protein Name | natriuretic peptide A |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24602 |
| Gene Symbol | Nppa |
| UniProt | P01161 (ANF_RAT), B0BMW5 (B0BMW5_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
790
Total Number of Articles : 1653 |
Description |
natriuretic peptide A |
| Gene Summary |
Enables hormone activity. Involved in several processes, including cGMP biosynthetic process; cellular response to mechanical stimulus; and regulation of ion transport. Acts upstream of or within receptor guanylyl cyclase signaling pathway. Located in several cellular components, including brush border; mast cell granule; and perinuclear region of cytoplasm. Used to study congestive heart failure; pulmonary hypertension; and ureteral obstruction. Biomarker of acute kidney failure; artery disease (multiple); hypertrophic cardiomyopathy; and nephrosis. Human ortholog(s) of this gene implicated in artery disease (multiple); heart conduction disease (multiple); and peritonitis. Orthologous to human NPPA (natriuretic peptide A). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |