Protein Name natriuretic peptide A
Organism Rattus norvegicus
Gene ID 24602
Gene Symbol


UniProt P01161 (ANF_RAT), B0BMW5 (B0BMW5_RAT)
Relationships Total Number of functionally related compound(s) : 790
Total Number of Articles : 1653

natriuretic peptide A

Gene Summary

Enables hormone activity. Involved in several processes, including cGMP biosynthetic process; cellular response to mechanical stimulus; and regulation of ion transport. Acts upstream of or within receptor guanylyl cyclase signaling pathway. Located in several cellular components, including brush border; mast cell granule; and perinuclear region of cytoplasm. Used to study congestive heart failure; pulmonary hypertension; and ureteral obstruction. Biomarker of acute kidney failure; artery disease (multiple); hypertrophic cardiomyopathy; and nephrosis. Human ortholog(s) of this gene implicated in artery disease (multiple); heart conduction disease (multiple); and peritonitis. Orthologous to human NPPA (natriuretic peptide A). [provided by Alliance of Genome Resources, Apr 2022]

  • natriuretic peptides A
  • Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd)
  • atrial natriuretic factor prohormone
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