Pub. Date : 1991 Mar 15
PMID : 1706539
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chlordecone (CD) pretreatment is well known to greatly potentiate CCl4 toxicity. | Chlordecone | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 2 | Chlordecone (CD) pretreatment is well known to greatly potentiate CCl4 toxicity. | Chlordecone | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 3 | Without cyanidanol, CD + CCl4 combination caused 50 and 100% lethality after CCl4 (L) and the standard dose, respectively, while the same doses of CCl4 alone did not cause lethal effects. | Chlordecone | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 4 | Without cyanidanol, CD + CCl4 combination caused 50 and 100% lethality after CCl4 (L) and the standard dose, respectively, while the same doses of CCl4 alone did not cause lethal effects. | Chlordecone | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 5 | The combination of CD + standard dose of CCl4 resulted in progressive and marked elevations of all three serum enzymes at all time intervals until the death of animals. | Chlordecone | C-C motif chemokine ligand 4 | Rattus norvegicus |
| 6 | However, CCl4 challenge to rats maintained on CD resulted in progressive injury, characterized by the appearance of ballooned cells, necrotic cells, and cells with lipid droplets in the liver. | Chlordecone | C-C motif chemokine ligand 4 | Rattus norvegicus |