Protein Name C-C motif chemokine ligand 4
Organism Rattus norvegicus
Gene ID 116637
Gene Symbol

Ccl4

UniProt P50230 (CCL4_RAT), G3V7I1 (G3V7I1_RAT)
Relationships Total Number of functionally related compound(s) : 1334
Total Number of Articles : 2238
Description

C-C motif chemokine ligand 4

Gene Summary

Enables chemokine activity. Involved in several processes, including leukocyte chemotaxis; positive regulation of tumor necrosis factor production; and positive regulation of vascular permeability. Predicted to be active in extracellular space. Biomarker of anti-basement membrane glomerulonephritis; obesity; and status epilepticus. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL4L2 (C-C motif chemokine ligand 4 like 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • C-C motif chemokine 4
  • MIP-1-beta
  • chemokine (C-C motif) ligand 4
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Properties