Pub. Date : 2006 Nov 10
PMID : 16951403
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lag1 (longevity assurance gene 1) homologues, a family of transmembrane proteins found in all eukaryotes, have been shown to be necessary for (dihydro)ceramide synthesis. | dihydroceramide | ceramide synthase 1 | Homo sapiens |
| 2 | Lag1 (longevity assurance gene 1) homologues, a family of transmembrane proteins found in all eukaryotes, have been shown to be necessary for (dihydro)ceramide synthesis. | dihydroceramide | ceramide synthase 1 | Homo sapiens |
| 3 | However, the functional significance of the conserved Lag1p motif for (dihydro)ceramide synthesis is currently unknown. | dihydroceramide | ceramide synthase 1 | Homo sapiens |
| 4 | In addition, our results showed that C18:0 fatty acid CoA (but not cis-C18:1 fatty acid CoAs) are substrates for LASS1 and that LASS1 in HeLa cells is sensitive to fumonisin B1, an in vitro inhibitor of (dihydro)ceramide synthase. | Fatty Acids | ceramide synthase 1 | Homo sapiens |
| 5 | In addition, our results showed that C18:0 fatty acid CoA (but not cis-C18:1 fatty acid CoAs) are substrates for LASS1 and that LASS1 in HeLa cells is sensitive to fumonisin B1, an in vitro inhibitor of (dihydro)ceramide synthase. | fumonisin B1 | ceramide synthase 1 | Homo sapiens |