Title : Effective attenuation of acute lung injury in vivo and the formyl peptide-induced neutrophil activation in vitro by CYL-26z through the phosphoinositide 3-kinase gamma pathway.

Pub. Date : 2006 Sep 14

PMID : 16887102






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These results indicate that the blockade of Ras activation by CYL-26z attenuated the downstream phosphoinositide 3-kinase (PI3K) gamma signaling, which is involved in chemoattractant-induced neutrophil chemotaxis and respiratory burst, and may have a beneficial anti-inflammatory effect on ALI. 5-(4-acridin-9-ylamino)phenyl-5-methyl-3-methylenedihydrofuran-2-one phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Mus musculus