Title : SIRT1 stimulation by polyphenols is affected by their stability and metabolism.

Pub. Date : 2006 Jul

PMID : 16603228






2 Functional Relationships(s)
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Protein Name
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1 Epigallocatechin galate (EGCg, 1.76-fold), epicatechin galate (ECg, 1.85-fold) and myricetin (3.19-fold) stimulated SIRT1 under stabilizing conditions, whereas without stabilization, these polyphenols strongly inhibited SIRT1, probably due to H2O2 formation. myricetin sirtuin 1 Homo sapiens
2 Epigallocatechin galate (EGCg, 1.76-fold), epicatechin galate (ECg, 1.85-fold) and myricetin (3.19-fold) stimulated SIRT1 under stabilizing conditions, whereas without stabilization, these polyphenols strongly inhibited SIRT1, probably due to H2O2 formation. myricetin sirtuin 1 Homo sapiens