Title : The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease.

Pub. Date : 2006 Apr 4

PMID : 16567633






1 Functional Relationships(s)
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1 Rapamycin, an inhibitor of mTOR, is highly effective in reducing renal cystogenesis in two independent mouse models of PKD. Sirolimus mechanistic target of rapamycin kinase Mus musculus