Title : Fibroblast heterogeneity in collagenolytic response to cyclosporine.

Pub. Date : 1991 Jun

PMID : 1655819






2 Functional Relationships(s)
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1 In two of the subpopulations and in both strains at some concentrations, the effect of CS on the relative levels of collagenase and TIMP could account for the decreased collagenase activity; i.e., the level of collagenase was unchanged or decreased, and TIMP production was unchanged or increased. Cyclosporine TIMP metallopeptidase inhibitor 1 Homo sapiens
2 In two of the subpopulations and in both strains at some concentrations, the effect of CS on the relative levels of collagenase and TIMP could account for the decreased collagenase activity; i.e., the level of collagenase was unchanged or decreased, and TIMP production was unchanged or increased. Cyclosporine TIMP metallopeptidase inhibitor 1 Homo sapiens